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doi: 10.1038/srep41063 154 GonzalezASalillasSVelazquez-CampoyAEspinosa AngaricaVFillatMFSanchoJet al

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Sexually mature males only produce GnRH pulses (Figure 4), while females generate GnRH pulses and also trigger a GnRH surge during proestrus of the ovulatory cycle ( FIGURE 4 LH and FSH, which are released from the pituitary, act on G-protein-coupled receptors on the membranes of Leydig and Sertoli cells in the testes, respectively