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What AOD-9604 is, and what the evidence actually shows AOD-9604 is a 16-amino-acid synthetic peptide corresponding to the C-terminal fragment of human growth hormone, specifically the region responsible for the lipolytic (fat-mobilising) effects of GH [Heffernan et al., Endocrinology, 2001]

Oxidative stress and hypoxia modulate cellular networks via transcriptional regulators, such as HIF-1-mediated induction of BNIP3/NIX, to promote mitophagy, [] as well as through direct protein modifications, such as the redox-sensitive oligomerization of MFNs that regulates mitochondrial fusion

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