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Following incubation, cells were rinsed in PBS then incubated with WST-1 reagent (diluted 1:10 into fresh starved media (Roche, UK)) and incubated at 37 C for 4 h in a cell culture incubator according to manufacturers instructions

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Histone-derived peptides Histone proteins are among the primary targets of autoantibodies in lupus

The high levels of these adrenalin precursors can mean that if methylation is restored there can be a massive increase in the local production of adrenalin

Increased CHAC1 levels induce ferroptosis and inhibit GC cell proliferation and survival, indicating that targeting the ATF4/CHAC1 axis could be a promising strategy for ferroptosis-based cancer therapy