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Dysbiosis promotes a shift in TRP metabolism away from 5-HT and toward KYN, QA, and 3-HK, while simultaneously impairing intestinal barrier integrity and driving low-grade systemic inflammation, exaggerated cortisol reactivity, HPA-axis dysregulation, visceral adiposity, and cardiometabolic risk all features commonly comorbid with depression [178,179,180,181,182]

The claim appears to derive from theoretical extrapolation rather than experimental evidence

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As well as the above, the clinical trial improved the ability of NK cells to kill their target two-fold, demonstrating a reduction in oxidative stress as well