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Meanwhile, when gut microbiota dysbiosis occurs, it may reduce ferroptosis-protective metabolites (such as 5-HT and 3-HAA) and increase ferroptosis-promoting metabolites (such as TMAO and LPS)

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Our results also demonstrate that the levels of several UFAs (nervonic acid, linoleic acid, alpha-linolenic acid, trans-vaccenic acid and palmitoleic acid) correlated with worse prognosis of COVID-19