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Yalniz F, Kantarjian HM, Borthakur G, Kadia TM, Daver NG, Pemmaraju N, Konopleva MY, Garcia-Manero G, Takahashi K, DiNardo CD, Bose P, Andreeff M , Ravandi F, Cortes JE

doi: 10.1007/978-1-0716-3601-5_10 68 PoojaryMMLundMNBarbaFJ

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These microbial-related changes may play a beneficial role, where PS23 may increase 5-hydroxytryptamine (5-HT) levels in the hippocampus, improve spatial memory impairment and motor function, and modulate age-related genes in aging mice (Cheng et al., 2022)

The reason why is because the majority of growth hormone secretion happens during sleep, so if you're not getting adequate amounts, or not getting adequate slow-wave sleep, your growth hormone levels are going to suffer along with your ability to build and maintain muscle mass