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Glucagon-like peptide-1 reduces pancreatic -cell mass through hypothalamic neural pathways in high-fat diet-induced obese rats

The reduced form is the most bio-available and the common dosage is 100 to 200 mg per day

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Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor