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EDR has been discussed in relation to expression of FNDC5, the precursor associated with irisin

Intraperitoneal injection of clodronate liposomes eliminates visceral adipose macrophages and blocks high-fat diet-induced weight gain and development of insulin resistance

Given the fact that Sm PoMucs are found associated with the apical glands and E/S products of miracidia and sporocysts, Sm PoMucs variability should be considered a key mechanism by which the parasite discourages recognition by key humoral immune complexes both at the surface of the parasite and in the surrounding tissues (18, 19, 40, 41)