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In addition, some investigators found that USP22 and lncRNA PART1 expression was decreased in a MIR injury model

Studies have found that Trx has a differential inhibitory effect on MMP-9, MMP-2, TIMP-1 and TIMP-2, thereby regulating the MMP/TIMP balance

If peripheral indices parallel central metabolic defects, and perhaps also neuromorphometric and/or neuroimaging findings, then there exists the possibility that alterations in peripheral indices on longitudinal follow-up (repeated measures) can usefully reflect central membrane function over the course of illness