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Int J Parasitol (1997) 27:10259.10.1016/S0020-7519(97)00067-2 136 PastranaDVRaghavanNFitzGeraldPEisingerSWMetzCBucalaRet alFilarial nematode parasites secrete a homologue of the human cytokine macrophage migration inhibitory factor

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Although tesofensine did not have a significant effect on total 24-hour energy expenditure, it increased energy expenditure during the night period when adjusted for changes in body composition

Also, a substantial decrease in glutathione levels precedes the mitochondrial dysfunction and neuronal death found in Parkinsons disease, suggesting GSH depletion may initiate the subsequent impairment.It also suggests that increasing GSH levels may have potential benefit toward preventing diseases associated with mitochondrial dysfunction