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Among the pharmacological models of psychosis used in humans, exposure to low dose ketamine and to psychostimulant, such as amphetamine, cocaine or methamphetamine, have been considered with interest since they mimic several aspects of the psychotic symptoms in SCZ

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Though there is not a single specific serum or plasma biomarker for ALS, higher levels of serum neurofilament light chain (NfL), a neuron-specific marker of axonal degeneration, have been found to differentiate ALS from disease mimics, such as inflammatory demyelinating polyneuropathy or structural polyradiculopathy [78], and correlates with rate of progression in ALS as well as disease severity [79]