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In short, the gut microbiota influences brain function via the regulation of neurotransmitters and neurotrophic factors, maintenance of intestinal barrier and tight junction integrity, activation of enteric sensory afferents, production of bacterial metabolites, and modulation of mucosal immune responses [22]

Pfalzer AC, Choi SW, Tammen SA, et al

The mechanisms that make peptides effective for pollen allergies (mast cell stabilization, NF-kB suppression, immune regulation) apply to pet allergies as well

This helps keep histamine inside your cell vs getting out into the blood

Since the hippocampal cholinergic system is associated with long-term memory formation, these results prove that moderate to high doses of sulbutiamine are capable of enhancing long-term memory formation in mice