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Using MRI, a reduction of NP signal intensity and disc height as swell as a higher rate of disc herniation could be documented in 35% of the injected discs compared to 14% in the control group

Redox proteomics: understanding oxidative stress in the progression of age-related neurodegenerative disorders

Specifically, a high-fat and high-sugar diet increased the -amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid to N-methyl-D-aspartic acid receptor current ratio in medium spiny neurons and prolonged spontaneous glutamate-mediated currents, increased DA release and slower DA reuptake in the striatum, and reduced MOR-mediated synaptic plasticity (73)

Finally, dried ATRA-ATO-NPs were obtained by washing, centrifugation, and freeze-drying

Pathological conditions can further influence excretion