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Diana Isaacs, PharmD, clarifies: "Metformin doesn't usually cause hypoglycemia on its own unless it's taken in combination with insulin or other diabetes medications like sulfonylureas..." Diana Isaacs, PharmD, Cleveland Clinic Other factors, like skipping meals, insufficient carbohydrate intake, or excessive exercise, can also trigger low blood sugar

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At the end of last year I wrote about 10 medical breakthroughs from 2025 you can read it here: This year Ill start with 5 major clinical trials to watch in 2026

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So, where does estrogen enter the picture