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As a result, the cellular level of glutathione decreases

The release of oxidized phospholipids and their breakdown products acts as danger signals that activate inflammatory pathways

Hydrogels are often not strong enough and are prone to deformation, making it difficult to support weight-bearing joints such as the knee, so finding the optimal polymer concentration to achieve optimal biomechanical loading is a prerequisite

In vivo experiments We have performed in vivo experiments on adult volunteers with the protocol approved by the ethical committee of Politecnico di Milano (parere n 37/2020) and have recruited four volunteers (see Table 1)

10.1002/jsfa.4120 J