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A meta-analysis published in Obesity Reviews found that weight loss through various interventions (lifestyle changes, bariatric surgery, or pharmacotherapy) was associated with significant increases in total testosterone, with greater weight loss producing larger hormonal improvements (Corona et al., 2013, Obesity Reviews )

A substantially higher proportion of treated participants achieved 5%, 10%, 15%, and 20% weight loss, alongside significant improvements in physical function as measured by the IWQOL-Lite-CT score

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