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Importantly, the gut symptoms (abdominal pain, diarrhoea, weight loss, low-grade fever, sometimes rectal bleeding) may or may not be present at the time the mouth changes appear

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Nature 380:435439 Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS et al (2003) The VIVA trial: vascular endothelial growth factor in ischemia for vascular angiogenesis

Comment: One commenter stated that we should educate the MACs well in advance of the effective date of these new policies and suggested we consider a formal program memorandum to do so