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Multidisciplinary Approach to Brain Fog and Related Persisting Symptoms Post COVID-19

However, an important safety concern for the development of a SARS-CoV-2 vaccine or of antibody-based therapies is the potential risk of vaccine enhancement of the disease, also known as antibody-dependent enhancement (ADE) and enhanced respiratory disease (ERD) 23

Chronic inflammation Chronic inflammation is a slow process that operates in silence, with clinical consequences only apparent at later stages when the damage and resulting clinical sequelae are often irreversible (42)

J Neurochem 105:18491860