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Moreover, as standalone weight-management drugs, all three remain research-stage as of July 2026

The downstream effect is more dilated vessels and improved local blood flow in injury models

Acknowledgements This work was supported by the National Institute on Drug Addiction (NIDA) of the National Institute of Health (NIH), grants R01DA046487 (D.S., S.M., and J.A.J.), R21DA045884 (S.M