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10.1038/2201137a0 158 LiM.GuM.-M.LangY.ShiJ.ChenB

Digestive enzymes can help break down food more efficiently, preventing bloating and discomfort if you have leaky gut Peptides such as BPC-157 are effective for healing leaky gut when recommended under the care of a naturopathic or functional medicine physician

For someone with documented deficiency, on long-term metformin or a PPI, or with confirmed absorption problems, step up to a higher-potency option like Jarrow Methyl B-12 5,000 mcg under a clinician's guidance

But the mechanism is on solid ground, and practitioners already running this combination in their practice are reporting the kind of results you would expect from the biology