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SAR studies, coupled with X-ray crystallography and structural analysis, revealed that the binding mode of this inhibitor is quite different from known GSH-like compounds

doi: 10.1055/a-1184-8388 168 KozloskyDBarrettEAleksunesLM

Vu LD, Gevaert K, De Smet I

However, as Moncrieff and colleagues point out in an attractive systemic review, there is no convincing evidence that depression could be associated with or caused by lower serotonin concentrations or activity [94]