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McKinnon MC, Cusi AM, MacQueen GM

Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of T-cells

Since gain-of-function mutations in NLRP3 were demonstrated to cause a rare autoinflammatory disease termed cryopyrin-associated periodic syndrome, NLRP3 has emerged as key mediator of inflammation in mouse models for many common diseases, including atherosclerosis, Alzheimers disease and gout