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Quantitative modeling of selective lysosomal targeting for drug design

Additionally, emerging mitochondria-targeted compounds, such as SS-31 (elamipretide) and MitoQ, have demonstrated preclinical efficacy in reducing oxidative damage and restoring mitochondrial function in neuronal models of depression and E2 deficiency (139)

7-Hydroxymatairesinol (7-HMR) is a lignan originally derived from the knotwood of spruce trees, and it is metabolically related to the mammalian lignan enterolactone (61)

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