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Of the ZEPBOUND-treated patients in OSA clinical studies, 37.2% and 19.5% of patients developed antibodies that were cross reactive to native GIP and native GLP-1, respectively

Individual results may vary based on health status, lifestyle, and treatment frequency

The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

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One possibility is that supplementary vitamin B-12 was preferentially shunted to fetal tissues and therefore did not result in improved maternal vitamin B-12 status