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2023;35:e2212300

[DOI] [PubMed] [Google Scholar] 123.Tzvetkov M.V., Matthaei J., Pojar S., Faltraco F., Vogler S., Prukop T., Seitz T., Brockmller J

As a result, Tyk2 knockout mice exhibited reduced proliferation of autoreactive CD8+ T cells and impaired cytotoxic activity against cells (122)

Active DNA demethylation mainly occurs by the removal of 5-methylcytosine via the sequential modification of cytosine bases that have been converted by TET enzyme-mediated oxidation