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M1-type macrophages primarily release pro-inflammatory factors, while M2-type macrophages produce anti-inflammatory cytokines such as IL-4, IL-10, and IL-13 within tumors (Murray et al., 2014)

The predominant p53 mutations observed in RA are missense mutations, namely transition mutations characterized by G:C to A:T substitutions

Structure GHK-Cu Sequence : Glycyl-L-histidyl-L-lysine Molecular Formula : C14H24N6O4Cu Molecular Weight : 401.94 g/mol PubChem CID : 5311164 TB-500 Sequence : Acetyl-Ser-Asp-Lys-Pro-Thr Molecular Formula : C12H21N3O6 Molecular Weight : ~496.5 g/mol PubChem CID : Not available BPC-157 Sequence : Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val Molecular Formula : C62H98N16O22 Molecular Weight : 1419.54 g/mol PubChem CID : 17757869 Citations for GLOW: GHK-Cu, TB-500, and BPC-157 Blend Citations for GHK-Cu Pickart, L., & Thaler, M

Lippincott Williams and Wilkins, Philadelphia, PA Gruenwald J (2004) PDR for herbal medicines

[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Mehansho H., Hamm M.W., Henderson L.M