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Retrieved May 6, 2025, from MedIndia

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These results generally agree with other studies in patients with severe mental illness, demonstrating that patients who carry variants that decrease MTHFR enzyme activity have higher rates of metabolic risk factors for CVD ( MTHFR 677 T allele were associated with significantly higher rates of metabolic syndrome diagnosis and that variant carrier status was also associated with increased HOMA-IR value ( MTHFR 677 T allele was associated with higher rates of metabolic syndrome ( MTHFR 677 T allele ( MTHFR 677 T variant, but the MTHFR 1298 C variant (or CC homozygote) was associated with metabolic syndrome prevalence ( MTHFR gene known to cause reduced enzyme function are associated with higher risk of cardiovascular disease

Nakhal et al., 2025b)

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