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Conversely, in cancer settings, Ashwagandha mounts a multi-faceted antitumor response, with well-documented cytotoxic effects across a range of cell lines, including breast, colon, lung, central nervous system, and leukemia cells [81, 207, 208]

Cryogenic electron microscopy (cryoEM) structural analyses revealed that E27 replaces endogenous CRL4 substrate receptors, resulting in proper positioning of STAT2 for polyubiquitylation and subsequent proteasomal destruction to inhibit host IFN signalling

Amino acid restriction triggers angiogenesis via GCN2/ATF4 regulation of VEGF and H(2)S production

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In a normal menstrual cycle, ovulation is triggered by a mid-cycle luteinizing hormone (LH) surge