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doi: 10.1016/j.cell.2007.08.012

In fact, proper records ensure compliance, support medical necessity, and reduce claim denials

A more sensitive method of screening for vitamin B 12 deficiency is measurement of serum methylmalonic acid and homocysteine levels, which are increased early in vitamin B 12 deficiency

Some patients may achieve adequate glycemic control or weight loss at this dose level, particularly those with mild metabolic dysfunction or those who are particularly sensitive to the medications effects

Therefore, this is a rare but life-threatening adverse event that needs critical and rapid management