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Find out which vitamins & supplements are helpful for macular degeneration (AMD), such as lutein, zeaxanthin, and others used in the AREDS studies

Competing interests The authors declare no competing interests

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6.2 Insufficient depth and integration of mechanistic studies Although existing studies have identified the involvement of multiple signaling pathwayssuch as AMPK, PPAR, SREBP, and FXRin hawthorn-mediated regulation of lipid metabolic homeostasis, most investigations remain confined to single-pathway validation and lack systematic analysis of the interactions among these pathways