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APAP hepatotoxicity occurs through formation of the noxious NAPQI metabolite, which is present in excessive quantities, as augmented by features of glutathione (GSH) depletion, oxidative stress and mitochondrial dysfunction leading to depletion in adenosine triphosphate (ATP) stores

Second, the GLDH enzyme uses oxidized cytochrome c as the only electron acceptor (Millar et al., 2003)

Micro-RNA detection based on fluorescence resonance energy transfer of DNA-carbon quantum dots probes

Saville et al., 2019