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The epigenetic modifications provide therapeutic opportunities to enhance CL function by using drugs which modify histone patterns or administer dietary substances that change epigenetic expressions (198)

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(2022) found that BBR modulates the GM and inhibits the initiation of the TLR4 signaling pathway, as well as the release of the nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome and its cytokines

Eussen SJ, de Groot LC, Clarke R, Schneede J, Ueland PM, Hoefnagels WH, et al: Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial