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In patients who had elevated level of serum lactate dehydrogenase (LDH) (key glycolysis rate-limiting enzyme), we found a moderate increase in the expression of hif-1 and lag-3 (Supplementary Fig

Owing to significant differences in metabolite concentrations, the detection of low-concentration metabolites demands increased sensitivity from these technologies

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Results over the nine trials were underwhelming, with most finding no impact from the antioxidants on peoples risk of developing cancer or the likelihood that they would survive it