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Since the MCD model clearly has its deficiencies in application with NASH pathology, researchers have developed modifications of this model to align the diet-induced phenotype more closely with human NASH

1 2 "Neuroenhancement with vitamin B12-underestimated neurological significance"

433 The adipocytes of Friedreichs ataxia mice showed significantly reduced GPX4 expression, increased lipid peroxides, and significantly increased sensitivity to ferroptosis

CITED4 gene therapy protects against maladaptive cardiac remodeling after ischemia/reperfusion injury in mice

Among the detachment from ECM during the procedure of metastasis, cancer cells can undergo alterations in metabolic pathways harmful to survival, such as moderated glucose uptake, PPP flux, and ATP levels while promoting the producing of ROS (261)