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MYO5B mutations cause cholestasis with normal serum gamma-glutamyl transferase activity in children without microvillous inclusion disease

B., Appa, Y., Bhandarkar, S

Methods: We implemented siRNA and adenovirus-mediated Ybx1 overexpression in primary human and mouse hepatocytes, as well as continuous hepatocytes, to investigate the effect of Ybx1 modulation on PPAR mRNA levels

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