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This suggests that administration of high doses of GSH could overcome the increased lethality of viral engineered pox viruses enhanced with IL-4, since GSH does up-regulate Th1 cytokine production, with increased IL-12 and IFNy, and can decrease expression of IL-4

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Here is the core principle

thus influencing PERK signaling (Piacentini et al., 2018)

Our study aims to elucidate the physiological and molecular adaptive strategies of this plant to salt stress by integrating physiological measurements and transcriptomic analysis