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Like CaMKK2, the PKA signalling pathway is also considered to play a key role in the pathogenesis of bipolar disorder, as increased cyclic AMP levels and PKA activity have been frequently observed in post-mortem brains and peripheral cells of bipolar disorder patients [58,59,60,61]

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HerissonFFrodermannVCourtiesGRohdeDSunYVandoorneKet al

To visually demonstrate the expression patterns of intersection genes, bar plots were generated using the ggplot2 package in R, illustrating the differential expression of these genes between RA patients and healthy controls