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2020;318:L77386

To systematically identify 20S proteasome substrates under native conditions, we used an advanced mass spectrometry (MS) approach coupled to biochemical and cellular analysis

These secondary bile acids promote the uptake of dietary fatty acids and activate cell surface signaling and upregulate nuclear hormone receptor levels

Alzheimer disease pathology reduction The most extensive body of P21 research has been conducted in the 3xTg-AD mouse model, a transgenic strain that develops both amyloid-beta plaques and tau tangles, closely mimicking human Alzheimer disease pathology

In contrast, AtHTL unexpectedly did not interact with AtMAX2 in a KAR 1 -dependent manner