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Hence, this review explores the association of CD44 variant exon expression with clinical outcomes of patients undergoing chemotherapy, highlights their role in key cell death pathways regulation, provides critical analysis of therapeutic substances and clinical studies targeting CD44 and discusses directions for further development of CD44 targeted therapeutic strategies

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For Dictyostelium , this means that they should transition to a multicellular state, to form a spore that can survive this period of nutrient limitation, preserving the population

These effects were independent of acute sickness and linked to impaired cognition and motivation, particularly continuous attention and curiosity, through prolonged central amygdala activation

Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling