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A total of 500-600 primary leaves were collected, immediately submerged in 2 L RNA stabilization solution (10 mL water-saturated phenol (pH 2 log 2 FC higher expression relative to epiphytic and late apoplastic conditions

mTOR pathway modulation Nitric oxide system interaction (NOS pathway) Growth hormone receptor upregulation VEGFR2-Akt-eNOS axis activation (angiogenesis, vascular stability) Src-caveolin-1-eNOS pathway (antioxidant, HO-1 induction) ERK1/2 signaling pathway (proliferation, migration, vascular tube formation) Anti-inflammatory macrophage polarization (M1M2 shift, TNF-/IL-6/IFN- reduction) Neuromodulation (stabilizes acetylcholine, dopamine, serotonin, GABA) Research Findings Preclinical research into gastrointestinal healing represents the most extensively studied application area

The powerful antioxidant properties help improve skin clarity, reduce pigmentation, and enhance overall tone

doi: 10.4103/1673-5374.253507 433 ZhangZYangJLZhangLLChenZZChenJOCaoYGet al