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These happened due to neuronal atrophy and enhanced density of Nissl bodies and neurons of the hippocampus (70, 72)

Dietary intervention studies have shown that the MedDiet, with or without caloric restriction, may induce weight loss in individuals with overweight and obesity ( Beyond examination of weight changes, studies have reported changes in inflammatory cytokines and a decrease in comorbidities in association with a MedDiet, even without weight loss

The extracts were filtered through 0.45 m polyethersulfone membranes (Millex Syringe Filter, MilliporeSigma, Burlington, MA, USA)

Depletion of the GM leads to the loss of its mediated negative feedback control on BAs synthesis, reduced signaling to the FXR, elevated hepatic BAs concentrations, impaired biliary barrier function, and ultimately exacerbation of CLI [74]

Indian J Paediatr Dermatol