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Peroxynitrite can oxidize a wide variety of biomolecules, which, in turn, modulates cell signal transduction pathways, interferes with mitochondrial function, impairs DNA, and finally mediates necrosis and apoptosis in different cell types (Korkmaz et al., 2009)

This HO-1-dependent cytoprotective mechanism may explain much of BPC-157s observed ability to protect cells against ischaemia-reperfusion injury and oxidative damage across multiple tissue types simultaneously

If successful, it could provide a new foundation for pancreatic cancer treatment

Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism