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Peptides improve cellular signaling and efficiency, helping mitochondria produce more usable energy over time

Freezing extends this to 90 days but requires aliquoting into single-use portions to avoid freeze-thaw damage

L. I. Fedoreyeva, I. I. Kireev, V. Kh. Khavinson, and B. F. Vanyushin, Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA, Pleiades Publishing Ltd, Nov. 2011. doi: 10.1134/s0006297911110022

A recent paper using the zebrafish tailfin regeneration model demonstrated that Sonic hedgehog (Shh) a key signalling protein in the hedgehog signalling cascade acted downstream of NOX to increase SOD activity and H 2 O 2 production in the early stage of tailfin regeneration, most likely due to SOD oxidation 130

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