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The work still happens naturally, but with better support behind it

Nat Chem Biol 21:13971407

Would restoring mitochondrial functioning improve conditions associated with mitochondrial dysfunction? Challenges of Restoring Glutathione Restoring glutathione in cells was not straightforward because glutathione cannot work if taken orally for the same reasons that diabetic patients cannot eat insulin

No disease has been attributed to the loss of PrP expression in humans 16 and loss of one functional PRNP allele is compatible with life 17

The roles of these cells may still overlap, as there are cases of astrocytes phagocyting myelin, and microglia seems to be necessary in some cases of non-developmental oligodendrocyte maturation ( 2.2 Myelin destruction and neurodegeneration The central event in the CNS, related to IDDs, is the disruption of myelin turnover within parenchymal lesions