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The N-terminal tryptophan and three glycine residues give the molecule a flexible backbone that has not, in the published literature, been shown to adopt a stable secondary structure under physiological conditions

Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs

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2.1.2.2 Enzymatic ligation: Sortase Amediated covalent precision Sortase Amediated transpeptidation offers a site-specific covalent bond between an LPETG-tagged antigen and an N-terminal oligoglycine motif on the VLP surface (Figure 1C

This behaviour is reflected in a lower CSI of 0.44, indicating reduced overall skill compared to high cloud detection