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1:50), and nuclei with Hoechst 33342 (Invitrogen

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Furthermore, transformation into SCLC can occur in anaplastic lymphoma kinase (ALK)-positive lung cancer upon treatment with ALK-inhibitors and in wild-type EGFR or ALK NSCLC following immunotherapy [80, 81]

Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas

Activated NKT cells explosively secrete pro-inflammatory factors including IFN-, TNF-, and IL-17, while recruiting neutrophils and monocytes via chemokine pathways, thereby exacerbating hepatic inflammation