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In the published literature the combination is investigated for body-weight reduction and glycemic control , on the hypothesis that engaging the amylin and GLP-1 pathways together influences appetite and energy balance more than either agent does alone [3]

[2] Kim J, Jung Y

[17] Using a variety of tasks including the open field, elevated zero maze, y-maze, object location test and forced swim test, they found that CBD treatment following ischemic stroke resulted in reduced stroke-induced anxiety in the open field and elevated zero mazes, improved performance in the object location test and y-maze, and reduced depression-like symptoms in the forced swim test

Timing relative to exercise also matters

Ipamorelin is preferred partly because it doesn't significantly affect appetite