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High levels may result in brain damage

Integrating multi-mechanistic agents (e.g., curcumins dual iron chelation and A inhibition, CNB-001s synergistic antioxidant and anti-inflammatory effects) may improve efficacy while reducing required doses, thereby minimizing off-target risks

Mammalian Prdx6 is primarily a cytosolic protein (where peroxidase activity is maximal) and is translocated to the acidic organelles like lysosomes and lamellar bodies 1,5 (for its aiPLA 2 activity) with the help of 14-3-3 chaperone 1,6,7

and finally, meat comes from animals that were directly supplemented with Vitamin B12, therefore, its better to cut out the middleman by not eating meat and taking Vitamin B12 supplements directly instead