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Researchers might explore this combination in models of severe metabolic dysfunction where both NAD+ depletion and poor mitochondrial health are present

Sex difference in incidence of bipolar and anxiety disorders: findings from the global burden of disease study 2021

In this case, youll want to take a closer look at other variables that can be breaking you out

Your provider should: Evaluate your medical history and current health status Order baseline lab work (IGF-1, metabolic panel, hormones) Determine an appropriate starting dose Monitor your progress with follow-up labs and consultations Adjust your protocol based on your response Be proactive in communicating with your provider about your response, any side effects, and your treatment goals

The combination of these drugs has never been tested, but given their lack of individual effects I would be surprised if they had any effect in combination