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(2) Universidade Federal de Alfenas, Ouro Preto, MG, Brasil Diabetology & Metabolic Syndrome 2026: PO166 Introduction: Adequate dietary intake is essential in managing type 2 diabetes mellitus (T2DM), especially among older adults, who are more susceptible to metabolic changes and nutritional deficiencies

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Mutations in genes encoding enzymes of the UPS result in renal disease, and mutations in kidney-specific genes result in ubiquitinproteasome dysfunction that leads to renal disease

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There are, however, minor genetic mutations that can influence how someone might respond differently to the same diet and lifestyle as someone else, such as the MTHFR gene mutation